Show news: from last 30 days (default), 60 days, 90 days, last visit or all

Cannabis scheduling review

11th July 2018

The chief medical officer for England has reviewed the evidence for cannabis-based medicinal products and has recommended that they should be moved out of a schedule 1 classification. This review forms part of a series of measures looking at the scheduling of cannabis.

click here to view

Diamorphine 5mg and 10mg injection shortage update

11th July 2018

An update to the diamorphine injection shortage (see our previous news item in May 2018) is available from the Pharmaceutical Services Negotiating Committee (PSNC) website.

click here to view

Resources to support safer modification of food and drink

28th June 2018

A resource patient safety alert has been issued to eliminate use of the imprecise term ‘soft diet’ and assist with the safe transition to the International Dysphagia Diet Standardisation Initiative (IDDSI) framework, which introduces standard terminology to describe texture modification for food and drink.

Note. Information about swallowing capsules and tablets is included in the frequently asked questions section of the IDDSI website.

click here to view

MHRA alert: Denosumab

28th June 2018

The UK MHRA has sent out two drug safety updates regarding denosumab use:

Note. This information is included in the new on-line PCF denosumab monograph, which will be available shortly.

MHRA valproate prescribing resources available

27th June 2018

Resources and further information are now available from the MHRA and Royal Pharmaceutical Society (RPS) to support the prescribing of valproate in women and girls of child-bearing potential under the conditions of the pregnancy prevention programme (see our news item MHRA: Valproate updated contra-indications).

MHRA resources

RPS resources

FDA approves cannabidiol oral solution

26th June 2018

The US FDA has approved a cannabidiol (CBD) oral solution (Epidiolex) for the treatment of seizures associated with Lennox-Gastaut syndrome and Dravet syndrome. This is the first approved product that contains purified CBD from the Cannabis sativa plant without the psychoactive tetrahydrocannabinol (THC) component. A marketing authorization application has been submitted to the European Medicines Agency for this product and indication, however it has not yet been authorized in the EU.

click here to view

FDA safety communication: OTC benzocaine products

24th June 2018

The US Food and Drug Administration (FDA) has warned that over-the-counter (OTC) oral drug products containing benzocaine should not be used to treat children <2 years because of the rare but potentially life-threatening risk of methemoglobinemia versus the little/lack of benefit for teething/oral pain.

click here to view

Danazol now contra-indicated with simvastatin

6th June 2018

The UK SPC for danazol capsules now contra-indicates concurrent use with simvastatin because of the risk of myopathy and rhabdomyolysis from increased simvastatin levels. Although not specifically contra-indicated, the risk if also increased with other statins metabolized by cytochrome P450 3A4 enzyme, e.g. atorvastatin, lovastatin.

click here to view

Diamorphine 5mg and 10mg injection shortage

23rd May 2018

Accord Pharmaceuticals has manufacturing difficulties with 5mg and 10mg diamorphine injection. The other UK supplier (Wockhardt) only has a small stock and is not expected to be able to keep up with the extra demand. It is expected that further supplies will be available from the 28 June 2018.

Diamorphine 30mg, 100mg and 500mg are not affected.

NHS organisations are strongly requested to order as normal and not to stockpile, as this will exacerbate the situation.

Website privacy policy and terms and conditions updated

23rd May 2018

Due to the upcoming change in EU data protection law, we have updated the terms and conditions and privacy policy on our website. These can be found via the links at the bottom of every page and we ask that you take a moment to read them. You can view and update your personal information at any time by logging on to the website and clicking on the preferences button. Here, you can also amend opting in or out to receiving e-mails from us, in line with the terms and conditions of use of the website.

Privacy policy (updated May 2018)

Terms and conditions (updated May 2018)