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MHRA alert: Valproate updated contra-indications

26th April 2018

Valproate must no longer be used in women or girls of child-bearing potential unless conditions of the pregnancy prevention programme are met, and only if other treatments are ineffective or not tolerated, as judged by a specialist. All women and girls of child-bearing potential currently taking valproate must be reviewed, provided with a patient guide and effective contraception as per the pregnancy prevention programme.

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